MemoHoney Official Website › Side Effects
Safety firstDoes MemoHoney Have Side Effects?
MemoHoney's seven rows are a B vitamin, a mineral and five amino acids at modest amounts, and the label names no specific side effect. The two effects this ingredient family is known for, niacin flushing and beta-alanine tingling, show up at doses several times what one capsule holds.
The label asks pregnant or nursing women, under-18s and anyone with a known medical condition to consult a physician first.
The label's caution in full, each row's known effects, the one interaction worth naming, and what to do if a capsule does not agree with you.
What the MemoHoney label's caution says
Printed on every bottle, next to the directions. Five instructions in four sentences.
“Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children. Do not use if safety seal is damaged or missing.”
Do not exceed the dose
One capsule a day. Two capsules is not a stronger routine, and it doubles the niacin toward its upper intake.
Pregnant or nursing
The label sends the question to a physician before the first capsule, and this desk follows the label.
Under 18
The label and this desk both set 18 as the floor. MemoHoney is an adult product.
A known medical condition
Heart, blood-pressure, kidney or liver conditions in particular, because of how arginine, citrulline and niacin act in the body.
MemoHoney side effects, row by row
Each row with the effect the research records and the amount where it appeared, beside the amount in one capsule.
| Panel row | Per capsule | What the research reports | Where the capsule sits |
|---|---|---|---|
| Niacin | 7.5 mg NE | Flushing, the warm red skin that set the 35 mg upper intake (IOM); serious effects only at gram doses (HPS2-THRIVE, a liver case). | About a fifth of the upper intake |
| Calcium | 18 mg | Constipation at high intakes, per the NIH fact sheet. | 1.5% of the Daily Value |
| L-Arginine + AKG | 400 mg | Stomach upset at gram doses. After a heart attack, the VINTAGE MI trial was stopped early. | A small fraction of trial doses |
| Arginine AKG alone | 200 mg | Tolerated at 12 g a day for eight weeks in trained men. | One sixtieth of that |
| L-Citrulline (two forms) | 200 mg | Lower blood pressure at 6 g a day and above (meta-analysis). | Far below the 6 g threshold |
| Beta Alanine | 40 mg | Paraesthesia, a harmless tingling, at larger single doses (ISSN, risk assessment). | Well under the tingle range |
Reported effects come from studies of each compound on its own, at the amounts those studies used.
The pattern across the table is reassuring: every effect that is well documented belongs to amounts many times larger than a capsule holds. The safety question for most adults is therefore not the capsule on its own. It is what the capsule adds to a medicine or a condition that already acts on blood pressure, which is the interaction below.
Medicines worth raising before MemoHoney
Arginine and citrulline act on nitric oxide. That is the interaction worth naming, and three kinds of medicine share it.
Blood-pressure medicines
Arginine and citrulline feed nitric oxide, which relaxes vessel walls. Added to a medicine that lowers blood pressure, the two push the same way.
Nitrates for chest pain
Nitroglycerin and similar drugs work by releasing nitric oxide. Anything that adds to the same signal belongs in the conversation first.
Erectile-dysfunction drugs
Sildenafil, tadalafil and their relatives act on the same nitric-oxide pathway, and they already carry warnings about combined blood-pressure effects.
Anyone taking blood-pressure medicines, nitrates or ED drugs should talk to their prescriber before the first capsule. Bring the panel: every amount is printed, which makes it an easy question to answer.
Who should not take MemoHoney without advice
Six groups for whom a conversation comes before the first capsule.
Anyone under 18
The label's floor, and this desk's. There is no children's version.
Pregnant or nursing women
The label asks for a physician's advice first, and this desk would not sell around that.
People after a heart attack
VINTAGE MI gave arginine after a heart attack and was stopped early. A cardiologist should decide.
People with low blood pressure
Nitric-oxide precursors lower pressure at higher doses. If yours already runs low, ask first.
Kidney or liver conditions
The kidneys recycle citrulline and the liver handles niacin. A known condition in either is a reason to check.
Anyone with a sudden memory change
A new or fast change in memory needs a doctor's assessment, not a supplement.
If MemoHoney does not agree with you
Four steps, in order. None of them involves pushing through.
- 1
Stop taking it
Supplements are optional. Stopping is the first step and costs nothing.
- 2
Write down what happened
What you felt, when, and what else you took that day. It helps whoever you speak to next.
- 3
Get advice if it is more than mild
A doctor, or emergency care for anything severe. The FDA explains how to report a reaction to a supplement in its questions and answers.
- 4
Use the guarantee
Call +1 (302) 200-3480 with the order ID. The 60-day window runs from the date of purchase; the guarantee page has the steps.
Counting niacin across MemoHoney and your other supplements
Niacin is the one ingredient here with an upper intake, so it is the one worth adding up if you take more than one supplement.
- 1
Read every label you take
Multivitamins, B-complex tablets, energy drinks and many fortified foods list niacin or niacinamide, in mg or mg NE. Note each amount.
- 2
Add the supplement amounts
Start with MemoHoney's 7.5 mg NE. The 35 mg upper intake in the Institute of Medicine review applies to niacin from supplements and fortified foods, added together.
- 3
Stay under 35 mg
If the total goes over, drop one of the other products. Do not split or skip MemoHoney capsules to make the sum work; one a day is the label's routine.
The niacin in meat, fish, grains and pulses does not count toward the upper intake: the flushing it was set on comes from added niacin. Eat normally, and count what comes in capsules, tablets, drinks and fortified products.
What else is in a MemoHoney capsule
Three ingredients sit outside the seven rows. They hold the capsule together, and they matter most to anyone checking for allergens.
Hypromellose
The capsule shell, made from plant cellulose. It is what the seller’s vegetarian mark rests on.
Vegetable stearate
A small amount of plant-derived fat that keeps the powder running evenly while the capsules are filled.
Silicon dioxide
An anti-caking agent, better known as silica, that keeps the powder loose inside each capsule.
Every ingredient on the panel and in the other-ingredients line is a vitamin, a mineral, an amino acid or a plant-derived capsule material, which matches the dairy-free, gluten-free and vegetarian marks in the seller’s artwork. The bottle label prints no allergen statement and none of those marks, so with a serious allergy, read the label wrap on the bottle that arrives and take it to your doctor or allergist before the first capsule.
Using MemoHoney safely day to day
Most of safe use is the label's own directions, followed exactly.
- One capsule a day with 8 oz of water, 20 to 30 minutes before a meal.
- Count all your niacin: MemoHoney is 7.5 mg NE of a 35 mg supplemental limit.
- Keep it in a cool, dry place away from heat and light, as the label asks.
- Check the safety seal before the first capsule; do not use a bottle with a damaged or missing seal.
- Keep the bottle out of reach of children.
- Start one new supplement at a time, as NCCIH advises, so a reaction can be traced.
MemoHoney safety questions
Does MemoHoney have side effects?
The label names no specific side effect. The effects known for this ingredient family, niacin flushing and beta-alanine tingling, appear at doses several times what one capsule holds. Stop if anything does not agree with you.
Can MemoHoney cause flushing?
Unlikely at 7.5 mg NE of niacin, which is about a fifth of the 35 mg upper intake set on flushing. Other niacin sources in the same day add to it.
Can I take MemoHoney with blood-pressure medicine?
Talk to your prescriber first. Arginine and citrulline act on nitric oxide, the same pathway that lowers blood pressure, as do nitrates and ED drugs.
Is MemoHoney safe during pregnancy?
The label asks pregnant or nursing mothers to consult a physician before use.
Can teenagers take MemoHoney?
No. It is for adults 18 and over.
What should I do if I react badly to MemoHoney?
Stop taking it, get medical advice if it is more than mild, and call +1 (302) 200-3480 with the order ID to use the 60-day guarantee.
Sources for the MemoHoney safety page
The reference intakes, trials and safety reviews behind each row above.
- Institute of Medicine (US) Standing Committee on the Scientific Evaluation of Dietary Reference Intakes. Niacin. In: Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington (DC): National Academies Press; 1998. Defines niacin equivalents (NE) and sets the adult tolerable upper intake at 35 mg/day from supplements, with flushing as the critical effect. NCBI Bookshelf NBK114304. https://www.ncbi.nlm.nih.gov/books/NBK114304/
- Haynes R, Valdes-Marquez E, Hopewell JC, et al. Serious Adverse Effects of Extended-release Niacin/Laropiprant: Results From the Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events (HPS2-THRIVE) Trial. Clin Ther. 2019;41(9):1767-1777. Niacin-laropiprant at 2,000/40 mg a day in 25,673 patients. PMID 31447131. https://pubmed.ncbi.nlm.nih.gov/31447131/
- Durham SH, Covington EW, Clemmons KJ. Hepatotoxicity upon using niacin to pass a drug test: A case report. J Am Pharm Assoc (2003). 2018;58(5):564-567. PMID 29941333. https://pubmed.ncbi.nlm.nih.gov/29941333/
- Calcium: Fact Sheet for Health Professionals. Office of Dietary Supplements, National Institutes of Health. https://ods.od.nih.gov/factsheets/Calcium-HealthProfessional/
- Schulman SP, Becker LC, Kass DA, et al. L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial. JAMA. 2006;295(1):58-64. L-arginine at a goal dose of 3 g three times daily for six months; the trial was stopped early. PMID 16391217. https://pubmed.ncbi.nlm.nih.gov/16391217/
- Campbell B, Roberts M, Kerksick C, et al. Pharmacokinetics, safety, and effects on exercise performance of L-arginine alpha-ketoglutarate in trained adult men. Nutrition. 2006;22(9):872-81. Four grams three times daily, 12 g/day for eight weeks. PMID 16928472. https://pubmed.ncbi.nlm.nih.gov/16928472/
- Barkhidarian B, Khorshidi M, Shab-Bidar S, et al. Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis. Avicenna J Phytomed. 2019;9(1):10-20. Doses ran 3 to 9 g/day, and only the arms at 6 g/day or more moved diastolic pressure. PMID 30788274. https://pubmed.ncbi.nlm.nih.gov/30788274/
- Trexler ET, Smith-Ryan AE, Stout JR, et al. International society of sports nutrition position stand: Beta-Alanine. J Int Soc Sports Nutr. 2015;12:30. Four to six grams daily for at least four weeks, with paraesthesia the one reported side effect. PMID 26175657. https://pubmed.ncbi.nlm.nih.gov/26175657/
- Dolan E, Swinton PA, Painelli VS, et al. A Systematic Risk Assessment and Meta-Analysis on the Use of Oral beta-Alanine Supplementation. Adv Nutr. 2019;10(3):452-463. PMID 30980076. https://pubmed.ncbi.nlm.nih.gov/30980076/
- Using Dietary Supplements Wisely. National Center for Complementary and Integrative Health, National Institutes of Health. https://www.nccih.nih.gov/health/using-dietary-supplements-wisely
- Questions and Answers on Dietary Supplements. U.S. Food and Drug Administration. https://www.fda.gov/food/information-consumers-using-dietary-supplements/questions-and-answers-dietary-supplements
